Unravelling the cellular networks that regulate proteotoxic stress

Protein synthesis fidelity is essential for proteome stability and for functional maintenance of cellular processes. Errors occur at frequencies around 10-4 under normal physiological conditions and are tolerated by cells. If the frequency of these basal errors increases, the mechanisms of protein q...

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Detalhes bibliográficos
Autor principal: Varanda, Ana Sofia Paulo Varanda (author)
Formato: doctoralThesis
Idioma:eng
Publicado em: 2017
Assuntos:
Texto completo:http://hdl.handle.net/10773/22243
País:Portugal
Oai:oai:ria.ua.pt:10773/22243