Unravelling the cellular networks that regulate proteotoxic stress
Protein synthesis fidelity is essential for proteome stability and for functional maintenance of cellular processes. Errors occur at frequencies around 10-4 under normal physiological conditions and are tolerated by cells. If the frequency of these basal errors increases, the mechanisms of protein q...
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| Format: | doctoralThesis |
| Language: | eng |
| Published: |
2017
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| Subjects: | |
| Online Access: | http://hdl.handle.net/10773/22243 |
| Country: | Portugal |
| Oai: | oai:ria.ua.pt:10773/22243 |