Decrease in APP and CP mRNA expression supports impairment of iron export in Alzheimer's disease patients

Alzheimer's disease (AD) is a neurodegenerative disorder of still unknown etiology and the leading cause of dementia worldwide. Besides its main neuropathological hallmarks, a dysfunctional homeostasis of transition metals has been reported to play a pivotal role in the pathogenesis of this dis...

Full description

Bibliographic Details
Main Author: Guerreiro, C (author)
Other Authors: Silva, B (author), Crespo, A (author), Marques, L (author), Costa, S (author), Timóteo, A (author), Marcelino, E (author), Maruta, C (author), Vilares, A (author), Matos, M (author), Couto, F (author), Faustino, P (author), Verdelho, A (author), Guerreiro, M (author), Herrero Valverde, A (author), Costa, C (author), Mendonça, A (author), Martins, M (author), Costa, L (author)
Format: article
Language:por
Published: 2015
Subjects:
Alzheimer disease
Homeostasis
Iron
Online Access:http://hdl.handle.net/10400.10/1494
Country:Portugal
Oai:oai:repositorio.hff.min-saude.pt:10400.10/1494

Internet

http://hdl.handle.net/10400.10/1494

Similar Items