Validation of an analytical method using an anion-exchange monolithic column for the assessment of supercoiled plasmid DNA
The demand of high-purity supercoiled (sc) plasmid DNA (pDNA) to be applied as a vector for new therapeutic strategies, such as gene therapy or DNA vaccination has increased in the last years. Thus, it is necessary the implementation of an analytical technique suitable to control the quality of the...
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| Format: | masterThesis |
| Language: | eng |
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2015
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| Online Access: | http://hdl.handle.net/10400.6/2862 |
| Country: | Portugal |
| Oai: | oai:ubibliorum.ubi.pt:10400.6/2862 |