Role of the brain-derived neurotrophic factor at glutamatergic synapses

The neurotrophin brain-derived neurotrophic factor (BDNF) plays an important role in the activity-dependent regulation of synaptic structure and function, particularly of the glutamatergic synapses. BDNF may be released in the mature form, which activates preferentially TrkB receptors, or as proBDNF...

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Bibliographic Details
Main Author: Carvalho, A. L. (author)
Other Authors: Caldeira, M. V. (author), Santos, S. D. (author), Duarte, C. B. (author)
Format: article
Language:eng
Published: 2008
Subjects:
BDNF
TrkB
Glutamate
AMPA receptors
NMDA receptors
Spine density
Synaptic plasticity
Online Access:http://hdl.handle.net/10316/12652
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/12652

Internet

http://hdl.handle.net/10316/12652

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