In vitro 3D cell sheet-based model for unraveling scar pathophysiology

Fibroblasts are key players in the scarring process. In hypertrophic scars, fibroblasts suffer phenotypical changes into myofibroblasts persisting in the wound under the influence of local biochemical (TGFb1) and biomechanical signaling leading to enhanced immature extracellular matrix (ECM) synthes...

ver descrição completa

Detalhes bibliográficos
Autor principal: Rodrigues, Daniel Barreira (author)
Outros Autores: Moreira, Helena Rocha (author), Reis, R. L. (author), Marques, A. P. (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2017
Assuntos:
Texto completo:http://hdl.handle.net/1822/51923
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/51923