Imidazolidin-4-one derivatives of primaquine as novel transmission-blocking antimalarials

Imidazolidin-4-one derivatives of primaquine were synthesized as potential double prodrugs of the parent drug. The title compounds inhibit the development of the sporogonic cycle of Plasmodium berghei, affecting the appearance of oocysts in the midguts of the mosquitoes. The imidazolidin-4-ones are...

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Detalhes bibliográficos
Autor principal: Araujo, MJ (author)
Outros Autores: Bom, J (author), Capela, R (author), Casimiro, C (author), Chambel, P (author), Gomes, P (author), Iley, J (author), Lopes, F (author), Morais, J (author), Moreira, R (author), de Oliveira, E (author), do Rosario, V (author), Vale, N (author)
Formato: article
Idioma:eng
Publicado em: 2005
Assuntos:
Medicina básica
Basic medicine
Texto completo:https://hdl.handle.net/10216/82068
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/82068

Texto Completo

https://hdl.handle.net/10216/82068

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