Interaction of antitumoral fluorescent heteroaromatic compounds, a benzothienopyrrole and two thienoindoles, with DNA and lipid membranes

Three tricyclic compounds, a benzothieno[2,3-b]pyrrole 1, a thieno[3,2-f]indole 2 and a thieno[2,3-e]indole 3, early synthesized by us, were evaluated for their capacity to inhibit the in vitro growth of three human tumor cell lines, MCF-7 (breast adenocarcinoma), NCI-H460 (non-small cell lung cance...

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Bibliographic Details
Main Author: Abreu, Ana S. (author)
Other Authors: Castanheira, Elisabete M. S. (author), Coutinho, Paulo J. G. (author), Queiroz, Maria João R. P. (author), Ferreira, Paula M. T. (author), Silva, Luís A. Vale (author), Pinto, Eugénia (author)
Format: article
Language:eng
Published: 2012
Subjects:
Benzothienopyrrole
Thienoindole
Antitumor activity
Fluorescence
Lipid membranes
DNA binding
Science & Technology
Online Access:https://hdl.handle.net/1822/19590
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/19590

Internet

https://hdl.handle.net/1822/19590

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