Optimization approaches for the in silico discovery of optimal targets for gene over/underexpression

Metabolic engineering (ME) efforts have been recently boosted by the increase in the number of annotated genomes and by the development of several genome-scale metabolic models for microbes of interest in industrial biotechnology. Based on these efforts, strain optimization methods have been propose...

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Bibliographic Details
Main Author: Gonçalves, Emanuel (author)
Other Authors: Pereira, Rui (author), Rocha, I. (author), Rocha, Miguel (author)
Format: article
Language:eng
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1822/23370
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/23370