Glutathione Transferase A1-1: Catalytic Importance of Arginine 15

Glutathione transferases (GSTs) are fundamental enzymes of the cell detoxification system. They catalyze the nucleophilic attack Of glutathione (GSH) on electrophilic substrates to produce less toxic compounds. The resulting Substrate can then be recognized by ATP-dependent transmembrane PUMPS and c...

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Bibliographic Details
Main Author: Daniel F A R Dourado (author)
Other Authors: Pedro Alexandrino Fernandes (author), Bengt Mannervik (author), Maria Joao Ramos (author)
Format: article
Language:eng
Published: 2010
Subjects:
Online Access:https://hdl.handle.net/10216/96349
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/96349