Delivery of Splice Switching Oligonucleotides by Amphiphilic Chitosan-Based Nanoparticles

Splice switching oligonucleotides (SSOs) are a class of single-stranded antisense oligonucleotides (ssONs) being used as gene therapeutics and demonstrating great therapeutic potential. The availability of biodegradable and biocompatible delivery vectors that could improve delivery efficiencies, red...

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Bibliographic Details
Main Author: Moreno, PM (author)
Other Authors: Santos, J (author), Gomes, C (author), Varela-Moreira, A (author), Costa, A (author), Leiro, V (author), Mansur, H (author), Pêgo, AP (author)
Format: article
Language:eng
Published: 2016
Subjects:
chitosan
hydrophobic
nanoparticles
splice switching oligonucleotides
trimethylchitosan
Online Access:https://hdl.handle.net/10216/120740
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/120740

Internet

https://hdl.handle.net/10216/120740

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