Cyclooxygenase-2 expression on ifosfamide-induced hemorrhagic cystitis in rats

Purpose Hemorrhagic cystitis (HC) is a limiting side effect of chemotherapy with ifosfamide (IFS). In this study, we investigated the participation of cyclooxygenase-2 (COX-2) upon ifosfamide-induced HC. Methods Male Wistar rats (150-200 g; six rats per group) were treated with saline, IFS (400 mg/k...

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Detalhes bibliográficos
Autor principal: Macedo, Francisco Yuri Bulcao (author)
Outros Autores: Baltazar, Fátima (author), Almeida, Paulo Roberto Carvalho (author), Távora, Fábio (author), Ferreira, Francisco Valdeci (author), Schmitt, Fernando C. (author), Brito, Gerly Anne Castro (author), Ribeiro, Ronaldo Albuquerque (author)
Formato: article
Idioma:eng
Publicado em: 2008
Assuntos:
Animals
Cyclooxygenase 2
Cyclooxygenase 2 Inhibitors
Cystitis
Drug Therapy, Combination
Etoricoxib
Hemorrhage
Ifosfamide
Immunoenzyme Techniques
Indomethacin
Male
Mesna
Pentoxifylline
Protective Agents
Pyridines
Rats
Rats, Wistar
Sulfones
Thalidomide
Hemorrhagic cystitis
TNF-alfa
Myofibroblasts
TNF-alpha
Science & Technology
Texto completo:http://hdl.handle.net/1822/61604
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/61604

Texto Completo

http://hdl.handle.net/1822/61604

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