Evidence for an intramacrophage growth phase of Mycobacterium ulcerans

Mycobacterium ulcerans is the etiologic agent of Buruli ulcer (BU), an emerging tropical skin disease. Virulent M. ulcerans secretes mycolactone, a cytotoxic exotoxin with a key pathogenic role. M. ulcerans in biopsy specimens has been described as an extracellular bacillus. In vitro assays have sug...

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Detalhes bibliográficos
Autor principal: Torrado, Egídio (author)
Outros Autores: Fraga, Alexandra Gabriel (author), Castro, António G. (author), Stragier, Pieter (author), Meyers, Wayne M. (author), Portaels, Françoise (author), Silva, Manuel T. (author), Pedrosa, Jorge (author)
Formato: article
Idioma:eng
Publicado em: 2007
Assuntos:
Animals
Bacterial Toxins
Cells, Cultured
Disease Models, Animal
Female
Foot
Histocytochemistry
Humans
Macrolides
Macrophages
Mice
Mice, Inbred BALB C
Microscopy, Electron, Transmission
Mycobacterium Infections, Nontuberculous
Mycobacterium ulcerans
Phagocytosis
Skin Diseases, Bacterial
Skin Ulcer
Science & Technology
Texto completo:http://hdl.handle.net/1822/67769
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/67769

Texto Completo

http://hdl.handle.net/1822/67769

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