Evidence for an intramacrophage growth phase of Mycobacterium ulcerans

Mycobacterium ulcerans is the etiologic agent of Buruli ulcer (BU), an emerging tropical skin disease. Virulent M. ulcerans secretes mycolactone, a cytotoxic exotoxin with a key pathogenic role. M. ulcerans in biopsy specimens has been described as an extracellular bacillus. In vitro assays have sug...

Full description

Bibliographic Details
Main Author: Torrado, Egídio (author)
Other Authors: Fraga, Alexandra Gabriel (author), Castro, António G. (author), Stragier, Pieter (author), Meyers, Wayne M. (author), Portaels, Françoise (author), Silva, Manuel T. (author), Pedrosa, Jorge (author)
Format: article
Language:eng
Published: 2007
Subjects:
Animals
Bacterial Toxins
Cells, Cultured
Disease Models, Animal
Female
Foot
Histocytochemistry
Humans
Macrolides
Macrophages
Mice
Mice, Inbred BALB C
Microscopy, Electron, Transmission
Mycobacterium Infections, Nontuberculous
Mycobacterium ulcerans
Phagocytosis
Skin Diseases, Bacterial
Skin Ulcer
Science & Technology
Online Access:http://hdl.handle.net/1822/67769
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/67769

Internet

http://hdl.handle.net/1822/67769

Similar Items