A pair of peptides inhibits seeding of the hormone transporter transthyretin into amyloid fibrils

The tetrameric protein transthyretin is a transporter of retinol and thyroxine in blood, cerebrospinal fluid, and the eye, and is secreted by the liver, choroid plexus, and retinal epithelium, respectively. Systemic amyloid deposition of aggregated transthyretin causes hereditary and sporadic amyloi...

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Detalhes bibliográficos
Autor principal: Saelices, L. (author)
Outros Autores: Nguyen, B. (author), Chung, K. (author), Wang, Y. (author), Ortega, A. (author), Lee, J. (author), Coelho, T. (author), Bijzet, J. (author), Benson, M. (author), Eisenberg, D. (author)
Formato: article
Idioma:eng
Publicado em: 2020
Assuntos:
Texto completo:http://hdl.handle.net/10400.16/2392
País:Portugal
Oai:oai:repositorio.chporto.pt:10400.16/2392