CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity

Accurate chromosome segregation during mitosis requires precise coordination of various processes such as chromosome alignment, maturation of proper kinetochoremicrotubule (kMT) attachments, correction of erroneous attachments, and silencing of the spindle assembly checkpoint (SAC). How these fundam...

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Bibliographic Details
Main Author: Manning, AL (author)
Other Authors: Bakhoum, SF (author), Maffini, S (author), Melo, CC (author), Maiato, H (author), Compton, DA (author)
Format: article
Language:eng
Published: 2010
Subjects:
Cell cycle proteins
Cell Line
Tumor
Chromosomes
Microtubules
Mitosis
Mitotic spindle apparatus
Recombinant Fusion Proteins
Online Access:http://hdl.handle.net/10216/53790
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/53790

Internet

http://hdl.handle.net/10216/53790

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