Analysis of pro-apoptotic protein trafficking to and from mitochondria

Mitochondria play a key role in cell death and its regulation. The permeabilization of the outer mitochondrial membrane which is mainly controlled by proteins of the BCL-2 family, is a key event that can be directly induced by p53 and results in the release of pro-apoptotic factors to the cytosol, s...

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Bibliographic Details
Main Author: Vega-Naredo, Ignacio (author)
Other Authors: Cunha-Oliveira, Teresa (author), Serafim, Teresa L. (author), Sardão, Vilma A. (author), Oliveira, Paulo J. (author)
Format: article
Language:eng
Published: 2015
Subjects:
Animals
Apoptosis Regulatory Proteins
Cell Fractionation
Cell Line
Cell Nucleus
Cytosol
Electrophoresis, Polyacrylamide Gel
Fluorescent Dyes
Humans
Immunoblotting
Immunohistochemistry
Immunoprecipitation
Mice
Mitochondria
Protein Transport
Rats
Tissue Fixation
Online Access:http://hdl.handle.net/10316/41110
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/41110

Internet

http://hdl.handle.net/10316/41110

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