A transcription factor network specifying inhibitory versus excitatory neurons in the dorsal spinal cord

The proper balance of excitatory and inhibitory neurons is crucial for normal processing of somatosensory information in the dorsal spinal cord. Two neural basic helix-loop-helix transcription factors (TFs), Ascl1 and Ptf1a, have contrasting functions in specifying these neurons. To understand how A...

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Bibliographic Details
Main Author: Borromeo, M. D. (author)
Other Authors: Meredith, D. M. (author), Castro, D. S. (author), Chang, J. C. (author), Tung, K.-C. (author), Guillemot, F. (author), Johnson, J. E. (author)
Format: article
Language:eng
Published: 2015
Subjects:
ChIP-Seq
bHLH transcription factor
Dorsal neural tube
Neuronal subtype specification
Mouse
Chick
Ascl1
Ptf1a
Online Access:http://hdl.handle.net/10400.7/523
Country:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/523

Internet

http://hdl.handle.net/10400.7/523

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