A transcription factor network specifying inhibitory versus excitatory neurons in the dorsal spinal cord

The proper balance of excitatory and inhibitory neurons is crucial for normal processing of somatosensory information in the dorsal spinal cord. Two neural basic helix-loop-helix transcription factors (TFs), Ascl1 and Ptf1a, have contrasting functions in specifying these neurons. To understand how A...

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Detalhes bibliográficos
Autor principal: Borromeo, M. D. (author)
Outros Autores: Meredith, D. M. (author), Castro, D. S. (author), Chang, J. C. (author), Tung, K.-C. (author), Guillemot, F. (author), Johnson, J. E. (author)
Formato: article
Idioma:eng
Publicado em: 2015
Assuntos:
ChIP-Seq
bHLH transcription factor
Dorsal neural tube
Neuronal subtype specification
Mouse
Chick
Ascl1
Ptf1a
Texto completo:http://hdl.handle.net/10400.7/523
País:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/523

Texto Completo

http://hdl.handle.net/10400.7/523

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