Switching Axial Progenitors from Producing Trunk to Tail Tissues in Vertebrate Embryos

The vertebrate body is made by progressive addition of new tissue from progenitors at the posterior embryonic end. Axial extension involves different mechanisms that produce internal organs in the trunk but not in the tail. We show that Gdf11 signaling is a major coordinator of the trunk-to-tail tra...

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Bibliographic Details
Main Author: Jurberg, Arnon Dias (author)
Other Authors: Aires, Rita (author), Varela-Lasheras, Irma (author), Nóvoa, Ana (author), Mallo, Moisés (author)
Format: article
Language:eng
Published: 2016
Subjects:
Animals
Animals, Newborn
Base Sequence
Bone Morphogenetic Proteins
Bone and Bones
Growth Differentiation Factors
LIM-Homeodomain Proteins
Mesoderm
Mice
Mice, Transgenic
Molecular Sequence Data
Phenotype
Protein-Serine-Threonine Kinases
Receptors, Transforming Growth Factor beta
Signal Transduction
Stem Cells
Tail
Transcription Factors
Tretinoin
Body Patterning
Gene Expression Regulation, Developmental
Online Access:http://hdl.handle.net/10400.7/671
Country:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/671

Internet

http://hdl.handle.net/10400.7/671

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