In Situ Near-Infrared (NIR) Versus High-Throughput Mid- Infrared (MIR) Spectroscopy to Monitor Biopharmaceutical Production

The development of biopharmaceutical manufacturing processes presents critical constraints, with the major constraint being that living cells synthesize these molecules, presenting inherent behavior variability due to their high sensitivity to small fluctuations in the cultivation environment. To sp...

Full description

Bibliographic Details
Main Author: Sales, Kevin C. (author)
Other Authors: Rosa, Filipa (author), Sampaio, Pedro N. (author), Fonseca, LuÍs P. (author), B. Lopes, Marta (author), Calado, Cecília (author)
Format: article
Language:eng
Published: 2016
Subjects:
Biopharmaceuticals
Bioprocess monitoring
Mid-infrared spectroscopy
Near-infrared spectroscopy
Partial least squares models
PLS: Process analytical technologies
PAT
Online Access:http://hdl.handle.net/10400.21/6057
Country:Portugal
Oai:oai:repositorio.ipl.pt:10400.21/6057

Internet

http://hdl.handle.net/10400.21/6057

Similar Items