In Situ Near-Infrared (NIR) Versus High-Throughput Mid- Infrared (MIR) Spectroscopy to Monitor Biopharmaceutical Production

The development of biopharmaceutical manufacturing processes presents critical constraints, with the major constraint being that living cells synthesize these molecules, presenting inherent behavior variability due to their high sensitivity to small fluctuations in the cultivation environment. To sp...

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Detalhes bibliográficos
Autor principal: Sales, Kevin C. (author)
Outros Autores: Rosa, Filipa (author), Sampaio, Pedro N. (author), Fonseca, LuÍs P. (author), B. Lopes, Marta (author), Calado, Cecília (author)
Formato: article
Idioma:eng
Publicado em: 2016
Assuntos:
Biopharmaceuticals
Bioprocess monitoring
Mid-infrared spectroscopy
Near-infrared spectroscopy
Partial least squares models
PLS: Process analytical technologies
PAT
Texto completo:http://hdl.handle.net/10400.21/6057
País:Portugal
Oai:oai:repositorio.ipl.pt:10400.21/6057

Texto Completo

http://hdl.handle.net/10400.21/6057

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