Mutational profle of Brazilian lung adenocarcinoma unveils association of EGFR mutations with high Asian ancestry and independent prognostic role of KRAS mutations

Lung cancer is the deadliest cancer worldwide. The mutational frequency of EGFR and KRAS genes in lung adenocarcinoma varies worldwide per ethnicity and smoking. The impact of EGFR and KRAS mutations in Brazilian lung cancer remains poorly explored. Thus, we investigated the frequency of EGFR and KR...

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Bibliographic Details
Main Author: Leal, Letícia Ferro (author)
Other Authors: Paula, Flávia Escremim de (author), De Marchi, Pedro (author), Viana, Luciano de Souza (author), Pinto, Gustavo Dix Junqueira (author), Carlos, Carolina Dias (author), Berardinelli, Gustavo Noriz (author), Miziara, José Elias (author), Silva, Carlos Maciel da (author), Silva, Eduardo Caetano Albino (author), Pereira, Rui (author), Oliveira, Marco Antonio de (author), Scapulatempo-Neto, Cristovam (author), Reis, R. M. (author)
Format: article
Language:eng
Published: 2019
Subjects:
Science & Technology
Online Access:https://hdl.handle.net/1822/62502
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/62502

Internet

https://hdl.handle.net/1822/62502

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