The relevance of lipid accumulation in lysosomal storage diseases in immune cells function

Lysosomal storage diseases (LSDs) are rare genetic diseases in which different molecules accumulate in the lysosome due to defects in lysosomal proteins. Fabry disease, Gaucher disease and Niemann-Pick disease type C (NPC) are LSDs, sphingolipidoses in which there is the accumulation of different sp...

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Bibliographic Details
Main Author: Ribeiro, Helena Maria Moreira Ferreira Soares (author)
Format: doctoralThesis
Language:eng
Published: 2022
Subjects:
Lysosomal storage diseases
Lipid antigen presentation
CD1b
CD1d
Dendritic cells
Monocytes
Macrophages
Natural killer T cells
Online Access:http://hdl.handle.net/10773/30452
Country:Portugal
Oai:oai:ria.ua.pt:10773/30452

Internet

http://hdl.handle.net/10773/30452

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