A SYK/SHC1 pathway regulates the amount of CFTR in the plasma membrane

Mutations in the CFTR gene cause the recessive genetic disease Cystic Fibrosis, where the chloride transport across the apical membrane of epithelial cells mediated by the CFTR protein is impaired. CFTR protein trafficking to the plasma membrane (PM) is the result of a complex interplay between the...

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Bibliographic Details
Main Author: Loureiro, Claudia (author)
Format: conferenceObject
Language:eng
Published: 2020
Subjects:
Online Access:http://hdl.handle.net/10400.18/6944
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/6944