Modelling phagosomal lipid networks that regulate actin assembly

Background: When purified phagosomes are incubated in the presence of actin under appropriate conditions, microfilaments start growing from the membrane in a process that is affected by ATP and the lipid composition of the membrane. Isolated phagosomes ar. - DFG [Da 208/7-2, TR34]; BMBF ; Irvington...

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Detalhes bibliográficos
Autor principal: Kuehnel, Mark (author)
Outros Autores: Mayorga, Luis S. (author), Dandekar, Thomas (author), Thakar, Juilee (author), Schwarz, Roland (author), Anes, Elsa (author), Griffiths, Gareth (author), Reich, Jens (author)
Formato: article
Idioma:eng
Publicado em: 2015
Assuntos:
Mathematical & Computational Biology
Texto completo:http://hdl.handle.net/10451/21587
País:Portugal
Oai:oai:repositorio.ul.pt:10451/21587
Descrição
Resumo:Background: When purified phagosomes are incubated in the presence of actin under appropriate conditions, microfilaments start growing from the membrane in a process that is affected by ATP and the lipid composition of the membrane. Isolated phagosomes ar. - DFG [Da 208/7-2, TR34]; BMBF ; Irvington Institute CRI ; FEDER [POCI, PPCDT/BIA- BCM/55327/2004]; Alexander von Humboldt Foundation ; CONICET. - We thank J. Brouwers and B. Helms from Univ. Utrecht, Holland for communicating unpublished data on lipids in LBP phagosomes. This work was generously supported by DFG (Da 208/7-2; TR34), BMBF (Hepatosys, TD and JR; PathogenomikPlus, RS), the Irvington In

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