Conversion to sirolimus ameliorates cyclosporine-induced nephropathy in the rat – focus on serum, urine, gene and protein renal expression biomarkers

Protocols of conversion from cyclosporine A (CsA) to sirolimus (SRL) have been widely used in immunotherapy after transplantation to prevent CsA-induced nephropathy, but the molecular mechanisms underlying these protocols remain nuclear. This study aimed to identify the molecular pathways and putati...

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Bibliographic Details
Main Author: Sereno, José (author)
Other Authors: Nunes, Sara (author), Rodrigues-Santos, Paulo (author), Vala, Helena (author), Rocha-Pereira, Petronila (author), Fernandes, João (author), Santos-Silva, Alice (author), Teixeira, Frederico (author), Reis, Flávio (author)
Format: article
Language:eng
Published: 2014
Subjects:
Cyclosporine A
Transplantation
Sirolimus
Online Access:http://hdl.handle.net/10400.19/2180
Country:Portugal
Oai:oai:repositorio.ipv.pt:10400.19/2180

Internet

http://hdl.handle.net/10400.19/2180

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