Sustained release of a Streptococcus pneumoniae endolysin from liposomes for potential otitis media treatment

Local delivery of antimicrobials for otitis media treatment would maximize therapeutic efficacy while minimizing side effects. However, drug transport across the tympanic membrane in the absence of a delivery system is challenging. In this study, the MSlys endolysin was encapsulated in deformable li...

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Bibliographic Details
Main Author: Silva, Maria Daniela Ferreira (author)
Other Authors: Paris, Juan L. (author), Gama, F. M. (author), Silva, Bruno F. B. (author), Sillankorva, Sanna (author)
Format: article
Language:eng
Published: 2021
Subjects:
Online Access:http://hdl.handle.net/1822/74300
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/74300