Time course and mechanisms of left ventricular systolic and diastolic dysfunction in monocrotaline-induced pulmonary hypertension

Although pulmonary hypertension (PH) selectively overloads the right ventricle (RV), neuroendocrine activation and intrinsic myocardial dysfunction have been described in the left ventricle (LV). In order to establish the timing of LV dysfunction development in PH and to clarify underlying molecular...

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Detalhes bibliográficos
Autor principal: Correia-Pinto, Jorge (author)
Outros Autores: Henriques-Coelho, Tiago (author), Roncon-Albuquerque, Roberto (author), Lourenço, André P. (author), Rocha, Gustavo Filipe Melo Alves (author), Vasques-Nóvoa, Francisco (author), Gillebert, Thierry C. (author), Leite-Moreira, Adelino F. (author)
Formato: article
Idioma:eng
Publicado em: 2009
Assuntos:
Animals
Apoptosis
Collagen
Diastole
Disease Models, Animal
Endothelin-1
Hypertension, Pulmonary
Male
Monocrotaline
Myocardium
Myosin Heavy Chain
Peptidyl-Dipeptidase A
RNA, Messenger
Rats
Rats, Wistar
Systole
Tenascin-C
Time Factors
Ventricular Dysfunction, Left
Myocardial Contraction
Ventricular Pressure
Angiotensin-converting enzyme
Texto completo:http://hdl.handle.net/1822/67582
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/67582

Texto Completo

http://hdl.handle.net/1822/67582

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