Pessaries containing Nanostructured Lipid Carriers (NLC) for prolonged vaginal delivery of progesterone

Progesterone (PRG) plays a crucial role in the female reproductive system, being the vaginal route the most adequate for its administration, as this drug has an extensive hepatic first pass effect. Nonetheless, vaginal PRG dosage forms originate immediate drug release and requires repeated administr...

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Bibliographic Details
Main Author: Correia, A. (author)
Other Authors: Costa, C.P. (author), Silva, V. (author), Silva, R. (author), Lobo, J.M. Sousa (author), Silva, Ana Catarina (author)
Format: article
Language:eng
Published: 2021
Subjects:
Nanostructured lipid carriers
Progesterone
Pessaries
Vaginal delivery
Online Access:http://hdl.handle.net/10284/9818
Country:Portugal
Oai:oai:bdigital.ufp.pt:10284/9818

Internet

http://hdl.handle.net/10284/9818

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