p53 is required for etoposide-induced apoptosis of human embryonic stem cells
The molecular mechanisms controlling DNA-damage-induced apoptosis of human embryonic stem cells (hESC) are poorly understood. Here we investigate the role of p53 in etoposide-induced apoptosis. We show that p53 is constitutively expressed at high levels in the cytoplasm of hESC. Etoposide treatment...
| Main Author: | |
|---|---|
| Other Authors: | , |
| Format: | article |
| Language: | eng |
| Published: |
2008
|
| Online Access: | http://hdl.handle.net/10316/5299 |
| Country: | Portugal |
| Oai: | oai:estudogeral.sib.uc.pt:10316/5299 |