p53 is required for etoposide-induced apoptosis of human embryonic stem cells
The molecular mechanisms controlling DNA-damage-induced apoptosis of human embryonic stem cells (hESC) are poorly understood. Here we investigate the role of p53 in etoposide-induced apoptosis. We show that p53 is constitutively expressed at high levels in the cytoplasm of hESC. Etoposide treatment...
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| Outros Autores: | , |
| Formato: | article |
| Idioma: | eng |
| Publicado em: |
2008
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| Texto completo: | http://hdl.handle.net/10316/5299 |
| País: | Portugal |
| Oai: | oai:estudogeral.sib.uc.pt:10316/5299 |