Protective effect of carvedilol on chenodeoxycholate induction of the permeability transition pore

Intracellular accumulation of toxic, hydrophobic bile acids has been proposed as one of the putative final common pathways leading to cholestatic liver injury. Furthermore, bile acids have been proposed as a causative factor for hepatic cardiomyopathy. Hepatic tissue concentrations of chenodeoxychol...

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Bibliographic Details
Main Author: Rolo, Anabela P. (author)
Other Authors: Oliveira, Paulo J. (author), Moreno, António J. M. (author), Palmeira, Carlos M. (author)
Format: article
Language:eng
Published: 2001
Subjects:
Online Access:http://hdl.handle.net/10316/5428
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5428