Anti-EFG1 2-OMethylRNA oligomer inhibits Candida albicans filamentation and attenuates the candidiasis in Galleria mellonella

EFG1 is a central transcriptional regulator of filamentation that is an important virulence factor of Candida albicans. This study serves to assess in vivo the applicability of the anti-EFG1 2-OMethylRNA oligomer for inhibiting Candida albicans filamentation and to attenuate candidiasis, using the G...

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Bibliographic Details
Main Author: Araújo, Daniela (author)
Other Authors: Mil-Homens, Dalila (author), Henriques, Mariana (author), Silva, Sónia Carina (author)
Format: article
Language:eng
Published: 2022
Subjects:
2′-OMethyl chemical modification
antisense oligonucleotides
candidiasis
Galleria mellonella
virulence
Ciências Naturais::Ciências Biológicas
Science & Technology
Online Access:http://hdl.handle.net/1822/75282
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/75282

Internet

http://hdl.handle.net/1822/75282

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