Trade-Offs of Escherichia coli Adaptation to an Intracellular Lifestyle in Macrophages

The bacterium Escherichia coli exhibits remarkable genomic and phenotypic variation, with some pathogenic strains having evolved to survive and even replicate in the harsh intra-macrophage environment. The rate and effects of mutations that can cause pathoadaptation are key determinants of the pace...

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Detalhes bibliográficos
Autor principal: Azevedo, M (author)
Outros Autores: Sousa, A (author), Moura de Sousa, J (author), Thompson, J A (author), Proença, J T (author), Gordo, I (author)
Formato: article
Idioma:eng
Publicado em: 2016
Assuntos:
Cloning
Macrophages
Evolutionary adaptation
Intracellular pathogens
Bacterial evolution
Bacterial pathogens
Insertion mutation
Bacterial genetics
Texto completo:http://hdl.handle.net/10400.7/547
País:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/547

Texto Completo

http://hdl.handle.net/10400.7/547

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