Trade-Offs of Escherichia coli Adaptation to an Intracellular Lifestyle in Macrophages

The bacterium Escherichia coli exhibits remarkable genomic and phenotypic variation, with some pathogenic strains having evolved to survive and even replicate in the harsh intra-macrophage environment. The rate and effects of mutations that can cause pathoadaptation are key determinants of the pace...

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Bibliographic Details
Main Author: Azevedo, M (author)
Other Authors: Sousa, A (author), Moura de Sousa, J (author), Thompson, J A (author), Proença, J T (author), Gordo, I (author)
Format: article
Language:eng
Published: 2016
Subjects:
Cloning
Macrophages
Evolutionary adaptation
Intracellular pathogens
Bacterial evolution
Bacterial pathogens
Insertion mutation
Bacterial genetics
Online Access:http://hdl.handle.net/10400.7/547
Country:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/547

Internet

http://hdl.handle.net/10400.7/547

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