Synthesis, Structure and Antileishmanial Evaluation of Endoperoxide-Pyrazole Hybrids

Leishmaniases are among the most impacting neglected tropical diseases. In attempts to repurpose antimalarial drugs or candidates, it was found that selected 1,2,4-trioxanes, 1,2,4,5-tetraoxanes, and pyrazole-containing chemotypes demonstrated activity against Leishmania parasites. This study report...

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Detalhes bibliográficos
Autor principal: Amado, Patrícia S M (author)
Outros Autores: Costa, Inês C C (author), Paixão, José A (author), Mendes, Ricardo F (author), Cortes, Sofia (author), Cristiano, Maria L S (author)
Formato: article
Idioma:eng
Publicado em: 2022
Assuntos:
Texto completo:http://hdl.handle.net/10362/143678
País:Portugal
Oai:oai:run.unl.pt:10362/143678