Synthesis, Structure and Antileishmanial Evaluation of Endoperoxide-Pyrazole Hybrids

Leishmaniases are among the most impacting neglected tropical diseases. In attempts to repurpose antimalarial drugs or candidates, it was found that selected 1,2,4-trioxanes, 1,2,4,5-tetraoxanes, and pyrazole-containing chemotypes demonstrated activity against Leishmania parasites. This study report...

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Bibliographic Details
Main Author: Amado, Patrícia S M (author)
Other Authors: Costa, Inês C C (author), Paixão, José A (author), Mendes, Ricardo F (author), Cortes, Sofia (author), Cristiano, Maria L S (author)
Format: article
Language:eng
Published: 2022
Subjects:
Online Access:http://hdl.handle.net/10362/143678
Country:Portugal
Oai:oai:run.unl.pt:10362/143678