Stereoselective Synthesis of Orthogonally Protected 1,2-Diaminoinositols from D-Mannose

We present herein a promising novel strategy for the transformation of sugar aldehydes into 1,2-diaminoinositols. This process, based on the sequential intermolecular aza-Henry reaction and intermolecular Henry reaction allowed the total synthesis of a 1,2-diaminoinositols with total stereochemical...

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Bibliographic Details
Main Author: Acurcio, Rita C. (author)
Other Authors: Soengas, Raquel G. (author), Almeida Paz, Filipe A. (author), Silva, Artur M. S. (author)
Format: article
Language:eng
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10773/20528
Country:Portugal
Oai:oai:ria.ua.pt:10773/20528