Modulation of mitochondrial outer membrane permeabilization and apoptosis by ceramide metabolism

The yeast Saccharomyces cerevisiae undergoes a mitochondrial-dependent programmed cell death in response to different stimuli, such as acetic acid, with features similar to those of mammalian apoptosis. However, the upstream signaling events in this process, including those leading to mitochondrial...

Full description

Bibliographic Details
Main Author: Rego, António (author)
Other Authors: Costa, Margarida (author), Chaves, Susana Rodrigues (author), Matmati, Nabil (author), Pereira, Helena (author), Sousa, Maria João (author), Moradas-Ferreira, Pedro (author), Hannun, Yusuf A (author), Costa, Vítor (author), Côrte-Real, Manuela (author)
Format: article
Language:eng
Published: 2012
Subjects:
Acetic Acid
Animals
Apoptosis
Ceramides
Gene Deletion
Gene Expression Regulation, Fungal
Lipid Metabolism
Membrane Proteins
Mitochondria
Mitochondrial Membranes
Permeability
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Signal Transduction
Type C Phospholipases
Science & Technology
Online Access:http://hdl.handle.net/1822/63787
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/63787

Internet

http://hdl.handle.net/1822/63787

Similar Items