Cerebellar morphometric and spectroscopic biomarkers for Machado-Joseph Disease

Machado-Joseph disease (MJD) or Spinocerebellar ataxia type 3 (SCA3) is the most common form of dominant SCA worldwide. Magnetic Resonance Imaging (MRI) and Proton Magnetic Resonance Spectroscopy (1H-MRS) provide promising non-invasive diagnostic and follow-up tools, also serving to evaluate therapi...

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Bibliographic Details
Main Author: Miranda, Catarina Oliveira (author)
Other Authors: Nobre, Rui Jorge (author), Paiva, Vítor Hugo (author), Duarte, João Valente (author), Castelhano, João (author), Petrella, Lorena Itati (author), Sereno, José (author), Santana, Magda (author), Afonso, Sónia (author), Januário, Cristina (author), Castelo Branco, Miguel (author), Almeida, Luís Pereira de (author)
Format: article
Language:eng
Published: 2022
Subjects:
Machado-Joseph disease (MJD)
Spinocerebellar ataxia type 3 (SCA3)
Magnetic resonance imaging (MRI)
Proton magnetic resonance spectroscopy (1H-MRS) biomarkers
Motor performance
Animals
Biomarkers
Cerebellum
Glutamic Acid
Humans
Mice
Mice, Transgenic
Taurine
Machado-Joseph Disease
Online Access:http://hdl.handle.net/10316/102828
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/102828

Internet

http://hdl.handle.net/10316/102828

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