Modelling the onset of senescence at the G1/S cell cycle checkpoint
DNA damage (single or double-strand breaks) triggers adapted cellular responses. These responses are elicited through signalling pathways, which activate cell cycle checkpoints and basically lead to three cellular fates: cycle arrest promoting DNA repair, senescence (permanent arrest) or cell death....
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| Outros Autores: | , |
| Formato: | article |
| Idioma: | eng |
| Publicado em: |
2015
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| Assuntos: | |
| Texto completo: | http://hdl.handle.net/10400.7/339 |
| País: | Portugal |
| Oai: | oai:arca.igc.gulbenkian.pt:10400.7/339 |