Methyl-cyclopentadienyl Ruthenium Compounds with 2,2′-Bipyridine Derivatives Display Strong Anticancer Activity and Multidrug Resistance Potential

New ruthenium methyl-cyclopentadienyl compounds bearing bipyridine derivatives with the general formula [Ru(η5-MeCp)(PPh3)(4,4′-R-2,2′-bpy)]+ (Ru1, R = H; Ru2, R = CH3; and Ru3, R = CH2OH) have been synthesized and characterized by spectroscopic and analytical techniques. Ru1 crystallized in the mon...

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Detalhes bibliográficos
Autor principal: Mendes, Paulo J. (author)
Outros Autores: Corte-Real, Leonor (author), Teixeira, Ricardo (author), Gírio, Patrícia (author), Avecilla, Fernando Francisco (author), Marques, Fernanda Marujo (author), Robalo, Maria Paula Alves (author), Ramalho, João P. Prates (author), Garcia, Maria H. (author), Valente, Andreia (author), Falson, Pierre (author)
Formato: article
Idioma:por
Publicado em: 2019
Assuntos:
cyclopentadienyl ruthenium
Anticancer Activity
Multidrug Resistance
2,2′-Bipyridine
Texto completo:http://hdl.handle.net/10174/23865
País:Portugal
Oai:oai:dspace.uevora.pt:10174/23865

Texto Completo

http://hdl.handle.net/10174/23865

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