Methyl-cyclopentadienyl Ruthenium Compounds with 2,2′-Bipyridine Derivatives Display Strong Anticancer Activity and Multidrug Resistance Potential

New ruthenium methyl-cyclopentadienyl compounds bearing bipyridine derivatives with the general formula [Ru(η5-MeCp)(PPh3)(4,4′-R-2,2′-bpy)]+ (Ru1, R = H; Ru2, R = CH3; and Ru3, R = CH2OH) have been synthesized and characterized by spectroscopic and analytical techniques. Ru1 crystallized in the mon...

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Bibliographic Details
Main Author: Mendes, Paulo J. (author)
Other Authors: Corte-Real, Leonor (author), Teixeira, Ricardo (author), Gírio, Patrícia (author), Avecilla, Fernando Francisco (author), Marques, Fernanda Marujo (author), Robalo, Maria Paula Alves (author), Ramalho, João P. Prates (author), Garcia, Maria H. (author), Valente, Andreia (author), Falson, Pierre (author)
Format: article
Language:por
Published: 2019
Subjects:
cyclopentadienyl ruthenium
Anticancer Activity
Multidrug Resistance
2,2′-Bipyridine
Online Access:http://hdl.handle.net/10174/23865
Country:Portugal
Oai:oai:dspace.uevora.pt:10174/23865

Internet

http://hdl.handle.net/10174/23865

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