Effects of the functional HOTAIR rs920778 and rs12826786 genetic variants in glioma susceptibility and patient prognosis

Abnormal expression of the long non-coding RNA HOX transcript antisense intergenic RNA (HOTAIR) is oncogenic in several human cancers, including gliomas. The HOTAIR single nucleotide polymorphisms (SNPs) rs920778 (C > T) and rs12826786 (C > T) present in the intronic enhancer and promoter regi...

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Detalhes bibliográficos
Autor principal: Xavier-Magalhães, A (author)
Outros Autores: Oliveira, AI (author), Vieira de Castro, J (author), Pojo, M (author), Gonçalves, CS (author), Lourenço, T (author), Viana-Pereira, M (author), Costa, S (author), Linhares, P (author), Vaz, R (author), Nabiço, R (author), Amorim, J (author), Pinto, AA (author), Reis, RM (author), Costa, BM (author)
Formato: article
Idioma:eng
Publicado em: 2017
Assuntos:
Texto completo:http://hdl.handle.net/10400.23/1134
País:Portugal
Oai:oai:repositorio.hospitaldebraga.pt:10400.23/1134