Nuclear Magnetic Resonance (NMR) Study of the Effect of Cisplatin on the Metabolic Profile of MG-63 Osteosarcoma Cells

In the present study, (1)H HRMAS NMR spectroscopy was used to assess the changes in the intracellular metabolic profile of MG-63 human osteosarcoma (OS) cells induced by the chemotherapy agent cisplatin (CDDP) at different times of exposure. Multivariate analysis was applied to the cells spectra, en...

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Bibliographic Details
Main Author: Duarte, Iola F. (author)
Other Authors: Lamego, Inês (author), Marques, Joana (author), Marques, M. Paula M. (author), Blaise, Benjamin J. (author), Gil, Ana M. (author)
Format: article
Language:eng
Published: 2010
Subjects:
Alcohols
Amino Acids
Choline
Cisplatin
Humans
Kinetics
Lipids
Magnetic Resonance Spectroscopy
Metabolome
Osteosarcoma
Online Access:http://hdl.handle.net/10316/45103
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/45103

Internet

http://hdl.handle.net/10316/45103

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