Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies

α-Synuclein misfolding and aggregation is a hallmark in Parkinson’s disease and in several other neurodegenerative diseases known as synucleinopathies. The toxic properties of α-synuclein are conserved from yeast to man, but the precise underpinnings of the cellular pathologies associated are still...

Full description

Bibliographic Details
Main Author: Miranda, Hugo Vicente (author)
Other Authors: Szegő, Éva M. (author), Oliveira, Luís M. A. (author), Breda, Carlo (author), Darendelioglu, Ekrem (author), Oliveira, Rita M. de (author), Ferreira, Diana G. (author), Gomes, Marcos A. (author), Rott, Ruth (author), Oliveira, Márcia (author), Munari, Francesca (author), Enguita, Francisco J. (author), Simões, Tânia (author), Rodrigues, Eva F. (author), Heinrich, Michael (author), Martins, Ivo C. (author), Zamolo, Irina (author), Riess, Olaf (author), Cordeiro, Carlos (author), Ponces-Freire, Ana (author), Santos, Nuno C. (author), Lopes, Luisa V. (author), Xiang, Wei (author), Jovin, Thomas M. (author), Penque, Deborah (author), Engelender, Simone (author), Zweckstetter, Markus (author), Klucken, Jochen (author), Giorgini, Flaviano (author), Quintas, Alexandre (author), Outeiro, Tiago F. (author)
Format: article
Language:eng
Published: 2017
Subjects:
Glycation
Parkinson’s disease
Neurodegeneration
Alpha-synuclein
Online Access:http://hdl.handle.net/10400.26/19438
Country:Portugal
Oai:oai:comum.rcaap.pt:10400.26/19438

Internet

http://hdl.handle.net/10400.26/19438

Similar Items