MicroRNA‐181a restricts human γδ T cell differentiation by targeting Map3k2 and Notch2

γδ T cells are a conserved population of lymphocytes that contributes to anti-tumor responses through its overt type 1 inflammatory and cytotoxic properties. We have previously shown that human γδ T cells acquire this profile upon stimulation with IL-2 or IL-15, in a differentiation process dependen...

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Detalhes bibliográficos
Autor principal: Gordino, Gisela (author)
Outros Autores: Costa‐Pereira, Sara (author), Corredeira, Patrícia (author), Alves, Patrícia (author), Costa, Luís (author), Gomes, Anita Q. (author), Silva‐Santos, Bruno (author), Ribot, Julie C. (author)
Formato: article
Idioma:eng
Publicado em: 2021
Assuntos:
Cancer
Effector T lymphocytes
miR-181a
microRNAs
γδ T cells
Texto completo:http://hdl.handle.net/10400.21/14061
País:Portugal
Oai:oai:repositorio.ipl.pt:10400.21/14061

Texto Completo

http://hdl.handle.net/10400.21/14061

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