Mitochondrial disruption occurs downstream from β-adrenergic overactivation by isoproterenol in differentiated, but not undifferentiated H9c2 cardiomyoblasts: Differential activation of stress and survival pathways

β-Adrenergic receptor stimulation plays an important role in cardiomyocyte stress responses, which may result in apoptosis and cardiovascular degeneration. We previously demonstrated that toxicity of the β-adrenergic agonist isoproterenol on H9c2 cardiomyoblasts depends on the stage of cell differen...

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Bibliographic Details
Main Author: Branco, Ana F. (author)
Other Authors: Sampaio, Susana F. (author), Wieckowski, Mariusz R. (author), Sardão, Vilma A. (author), Oliveira, Paulo J. (author)
Format: article
Language:eng
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/10316/26910
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/26910