Cytotoxicity and Membrane Interaction of Tamoxifen as Affected by Ca2+ and Mg2+: Use of a Bacterial Model System

A strain of Bacillus stearothermophilus was used as a model to study the interaction of tamoxifen (TAM) with the membrane and the cytostatic antiproliferative effects not related to estrogen binding. TAM inhibits the growth of B. stearothermophilus as a function of concentration. The supplementation...

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Bibliographic Details
Main Author: Luxo, C. (author)
Other Authors: Jurado, A. S. (author), Madeira, V. M. C. (author)
Format: article
Language:eng
Published: 1999
Subjects:
Calcium
Magnesium
Tamoxifen
Bacillus stearothermophilus
Bacterial growth
Membrane physical effects
Online Access:http://hdl.handle.net/10316/5817
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5817

Internet

http://hdl.handle.net/10316/5817

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